Nucleotide series

Nicotinamide riboside chloride CAS 23111-00-4

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Nicotinamide riboside chloride CAS 23111-00-4

Nicotinamide nucleoside is a precursor of nicotinamide adenine dinucleotide (NAD) and represents the source of vitamin B3. Recent studies have shown that consuming larger amounts of nicotinamide nucleoside than naturally present in food can provide new health benefits. Nicotinamide mononucleotide plays an important role in energy production in human cells, as it participates in the synthesis of NAD (nicotinamide adenine dinucleotide, an important coenzyme for cellular energy conversion) within cells.

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Nicotinamide riboside chloride CAS 23111-00-4

Nicotinamide nucleoside has been involved in increasing tissue NAD concentration, inducing insulin sensitivity, and enhancing sirtuin function. Its ability to increase NAD production indicates that nicotinamide nucleoside can also improve mitochondrial health, stimulate mitochondrial function, and induce the production of new mitochondria. Other studies using nicotinamide nucleoside in Alzheimer's disease models have shown that the molecule is biologically available to the brain and may provide neuroprotective effects by stimulating brain NAD synthesis.

In addition, a 2012 study observed that mice fed a high-fat diet supplemented with nicotinamide nucleoside (nicotinamide nucleoside) had a 60% reduction in weight gain compared to mice fed the same high-fat diet without nicotinamide nucleoside. Nicotinamide nucleoside chloride (3-aminoformyl-1- [(2R, 3R, 4S5R) -3,4-dihydroxy-5- (hydroxymethyl) oxacyclopentan-2-yl] - pyridin-1-ium chloride); Also known as 1- (β - D-ribofuranosyl) nicotinamide chloride, it is a known salt form of nicotinamide nucleoside. Despite the useful properties of nicotinamide nucleoside and its chloride salts (such as in pharmaceuticals or nutritional supplements), improvements are often needed.

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