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Mannitol CAS 87-78-5

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Mannitol  CAS 87-78-5

Mannitol, also known as D-mannitol, is a functional sugar alcohol with superior properties. Widely used in industries such as pharmaceuticals, food, and chemicals.

There are currently two types of industrial production of mannitol: one is natural mannitol extracted from kelp as raw material, and the other is synthetic mannitol processed from sucrose and glucose as raw materials.




















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Mannitol  CAS 87-78-5

Application field
1. Food mannitol is one of the commonly used sugar alcohol and sugar substitutes, commonly used as an ingredient in sugar free chewing gum. Mannitol is the sugar alcohol with the lowest water absorption and can be used for food anti sticking powder. According to the hygiene standard GB2760-2007 for the use of food additives in China, they can be used on sugar free chewing gum with a maximum dosage of 200g/kg. As confirmed by JECFA, the ADI value ranges from 0 to 50mg/(kg body weight · d). The US FDA specifies the maximum usage of mannitol in various foods as follows: peppermint candy 98%, gummy candy 40%, hard candy 5%, candied fruits and ice cream 8%, cough syrup 5%, jam jelly 15%, gummy candy 31%, and other foods 2.5%. Mannitol is listed in the United States Pharmacopeia, the Natural Medicines section, as well as in pharmacopoeias around the world, including the Food Chemistry Handbook (FEC).
2. Medicine is used as a large infusion solution for injection, which is used to reduce brain pressure, intraocular pressure, and eliminate brain edema; Used as a diuretic; Renal function and intestinal examination; Due to edema and burns causing oliguria and renal failure, mannitol infusion has a certain therapeutic effect; Compound infusion with amino acids. Due to its excellent compression performance, it has become an excellent excipient for the pharmaceutical industry. In addition, mannitol nitrogen mustard and mannitol bis (methylsulfonic acid) synthesized from mannitol are anti-tumor drugs suitable for chronic leukemia and other conditions.
3. Chemical mannitol is esterified and etherified to produce various resins and surfactants. Mannitol ester can be used as a plasticizer for polyvinyl chloride; Polyurethane rigid foamed plastic based on polyether polymerized with epoxy propane can be used as heat insulation, sound insulation and moisture-proof materials.












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