Short Description:

L-carnitine 541-15-1

Brief introduction

Carnitine is a type of B vitamin with a structure similar to amino acids, so some people classify it as an amino acid. Its main function is to help transport long-chain fatty acids to provide energy. This can prevent fat accumulation in the heart, liver, and skeletal muscles. Artificially synthesized carnitine comes in three forms: L-carnitine, D-carnitine, and racemic carnitine, with L-carnitine showing better efficacy. L-carnitine is a compound with multiple physiological active functions, mainly responsible for promoting the β - oxidation of fatty acids; It can also regulate the ratio of acyl groups within mitochondria, affecting energy metabolism; L-carnitine can participate in the transportation of branched chain amino acid metabolites, thereby promoting the normal metabolism of branched chain amino acids. In addition, L-carnitine plays a role in the elimination and utilization of ketones, serving as a biological antioxidant to scavenge free radicals, maintain membrane stability, enhance animal immunity, and improve disease and stress resistance. Recent studies have shown that L-carnitine and acetyl-L-carnitine play important carrier roles in energy metabolism within sperm mitochondria, clearing ROS and protecting sperm membrane function. Oral administration of L-carnitine and acetyl-L-carnitine can increase the total number of forward motile sperm and motile sperm in patients with oligozoospermia and asthenozoospermia, improve the clinical pregnancy rate of females, and is safe and effective. Clinical trials at home and abroad have shown that carnitine treatment for male infertility is a new breakthrough in the field of male infertility drug therapy in recent years. It is necessary to conduct in-depth research to further elucidate its mechanism of action and clarify its indications.